Murine models of intestinal cancer : Recent advancesSHAW, Paul; CLARKE, Alan R.DNA repair. 2007, Vol 6, Num 10, pp 1403-1412, issn 1568-7864, 10 p.Article

Wnt-cadherin connections in normal and neoplastic mammary epitheliumMENIEL, Valerie; CLARKE, Alan R.Journal of mammary gland biology and neoplasia. 2003, Vol 8, Num 4, pp 435-447, issn 1083-3021, 13 p.Article

P53 null mice : damaging the hypothesis?SANSOM, Owen J; CLARKE, Alan R.Mutation research. 2000, Vol 452, Num 2, pp 149-162, issn 0027-5107Article

Gene manipulation through the use of small interfering RNA (siRNA) : From in vitro to in vivo applicationsLEKHA DINESH KUMAR; CLARKE, Alan R.Advanced drug delivery reviews. 2007, Vol 59, Num 2-3, pp 87-100, issn 0169-409X, 14 p.Article

p53 mediates a default programme of mammary gland involution in the absence of STAT3MATTHEWS, James R; CLARKE, Alan R.Oncogene (Basingstoke). 2005, Vol 24, Num 19, pp 3083-3090, issn 0950-9232, 8 p.Article

The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient miceSANSOM, Owen J; CLARKE, Alan R.Oncogene (Basingstoke). 2002, Vol 21, Num 38, pp 5934-5939, issn 0950-9232, 6 p.Article

Poly(ADP-Ribose) Polymerase-1 Inhibitor Treatment Regresses Autochthonous Brca2/p53-Mutant Mammary Tumors In vivo and Delays Tumor Relapse in Combination with CarboplatinHAY, Trevor; MATTHEW, James R; CLARKE, Alan R et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 9, pp 3850-3855, issn 0008-5472, 6 p.Article

A role for mismatch repair in control of DNA ploidy following DNA damageSTRATHDEE, Gordon; SANSOM, Owen J; SIM, Alyson et al.Oncogene (Basingstoke). 2001, Vol 20, Num 15, pp 1923-1927, issn 0950-9232Article

Entopic overexpression of Ascl2 does not accelerate tumourigenesis in Apc^Min miceREED, Karen R; TUNSTER, Simon J; YOUNG, Madeleine et al.Gut. 2012, Vol 61, Num 10, pp 1435-1438, issn 0017-5749, 4 p.Article

Analyzing tumor suppressor activities in the murine small intestineCLARKE, Alan R; SANSOM, Owen J.Oncology research. 2003, Vol 13, Num 6-10, pp 333-337, issn 0965-0407, 5 p.Conference Paper

Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiencyGALLAGHER, Ronald C. J; HAY, Trevor; MASON, John O et al.Oncogene (Basingstoke). 2002, Vol 21, Num 42, pp 6446-6457, issn 0950-9232, 12 p.Article

Crypt stem cells as the cells-of-origin of intestinal cancerBARKER, Nick; RIDGWAY, Rachel A; VAN ES, Johan H et al.Nature (London). 2009, Vol 457, Num 7229, pp 608-611, issn 0028-0836, 4 p.Article

MBD4 deficiency does not increase mutation or accelerate tumorigenesis in mice lacking MMRSANSOM, Owen J; BISHOP, Stefan M; BIRD, Adrian et al.Oncogene (Basingstoke). 2004, Vol 23, Num 33, pp 5693-5696, issn 0950-9232, 4 p.Article

PPARδ status and Apc-mediated tumourigenesis in the mouse intestineREED, Karen R; SANSOM, Owen J; HAYES, Anthony J et al.Oncogene (Basingstoke). 2004, Vol 23, Num 55, pp 8992-8996, issn 0950-9232, 5 p.Article

Single cell tracking reveals that Msh2 is a key component of an early-acting DNA damage-activated G2 checkpointMARQUEZ, Nuria; CHAPPELL, Sally C; SANSOM, Owen J et al.Oncogene (Basingstoke). 2003, Vol 22, Num 48, pp 7642-7648, issn 0950-9232, 7 p.Article

K-ras and Wnt Signaling Synergize to Accelerate Prostate Tumorigenesis in the MousePEARSON, Helen B; PHESSE, Toby J; CLARKE, Alan R et al.Cancer research (Chicago, Ill.). 2009, Vol 69, Num 1, pp 94-101, issn 0008-5472, 8 p.Article

Cyclin D2-Cyclin-Dependent Kinase 4/6 Is Required for Efficient Proliferation and Tumorigenesis following Apc LossCOLE, Alicia M; MYANT, Kevin; SANSOM, Owen J et al.Cancer research (Chicago, Ill.). 2010, Vol 70, Num 20, pp 8149-8158, issn 0008-5472, 10 p.Article

Deficiency of SPARC suppresses intestinal tumorigenesis in APC^Min/+ mice. CommentaryGREGORIEFF, Alex; CLEVERS, Hans; SANSOM, Owen J et al.Gut. 2007, Vol 56, Num 10, issn 0017-5749, 1341-1343, 1410-1414 [8 p.]Article

Brca2 deficiency in the murine small intestine sensitizes to p53-dependent apoptosis and leads to the spontaneous deletion of stem cellsHAY, Trevor; PATRICK, Teresa; WINTON, Douglas et al.Oncogene (Basingstoke). 2005, Vol 24, Num 23, pp 3842-3846, issn 0950-9232, 5 p.Article

Mutations in Apc and p53 synergize to promote mammary neoplasiaMENIEL, Valérie; HAY, Trevor; DOUGLAS-JONES, Anthony et al.Cancer research (Baltimore). 2005, Vol 65, Num 2, pp 410-416, issn 0008-5472, 7 p.Article

Apc deficiency predisposes to renal carcinoma in the mouseSANSOM, Owen J; GRIFFITHS, David F. R; REED, Karen R et al.Oncogene (Basingstoke). 2005, Vol 24, Num 55, pp 8205-8210, issn 0950-9232, 6 p.Article

New approaches for modelling cancer mechanisms in the mouseMADDISON, Kathryn; CLARKE, Alan R.Journal of pathology. 2005, Vol 205, Num 2, pp 181-193, issn 0022-3417, 13 p.Article

Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent mannerSANSOM, Owen J; TOFT, Neil J; WINTON, Douglas J et al.Oncogene (Basingstoke). 2001, Vol 20, Num 27, pp 3580-3584, issn 0950-9232Article

Suppression of intestinal and mammary neoplasia by lifetime administration of aspirin in Apc^Min/+ and apc^min/+, Msh2^-/- miceSANSOM, Owen J; STARK, Lesley A; DUNLOP, Malcolm G et al.Cancer research (Baltimore). 2001, Vol 61, Num 19, pp 7060-7064, issn 0008-5472Article

Focal Adhesion Kinase Is Required for Intestinal Regeneration and Tumorigenesis Downstream of Wnt/c-Myc SignalingASHTON, Gabrielle H; MORON, Jennifer P; NEUFELD, Kristi et al.Developmental cell. 2010, Vol 19, Num 2, pp 259-269, issn 1534-5807, 11 p.Article